DEPOD - human DEPhOsphorylation Database

Name	1-phosphatidyl-1D-myo-inositol 4-phosphate	Download: mol \| sdf
Synonyms	01,2-diacyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate); 1-phosphatidyl-1d-myo-inositol 4-monophosphate; 1-phosphatidyl-1d-myo-inositol 4-phosphate; Na; Phosphatidylinositol 4-phosphate; Pi4p; Pips; Ptdins(4)p; Ptdins-4-p; Ptdins4p;
Definition	A phosphatidylinositol 4-phosphate having 1D-myo-configuration.
Molecular Weight (Exact mass)	NA
Molecular Formula	C11H18O16P2R2
SMILES	[H][C@@](COC([])=O)(COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1O)OC([])=O
InChI	InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+
InChI Key	VWFJDQUYCIWHTN-YFVJMOTDSA-N
Crosslinking annotations	KEGG:C01277 \| ChEBI:17526 \| PubChem:4496

Pathway ID	Pathway Name	Pathway Description (KEGG)
map00562	Inositol phosphate metabolism	NA
map01100	Metabolic pathways	NA
map04070	Phosphatidylinositol signaling system	NA
map05134	Legionellosis	Legionellosis is a potentially fatal infectious disease caused by the bacterium Legionella pneumophila and other legionella species. Two distinct clinical and epidemiological syndromes are associated with Legionella species: Legionnaires' disease is the more severe form of the infection, which may involve pneumonia, and Pontiac fever is a milder respiratory illness.The pathogenesis of L. pneumophila is derived from its growth within lung macrophages. One of the L. pneumophila's type IV secretion systems, the Dot/Icm secretion system, is of critical importance for its ability to replicate and to cause disease. The Dot/Icm substrates modulate multiple host cell processes and in particular, redirect trafficking of the L. pneumophila phagosome and mediate its conversion into an ER-derived organelle competent for intracellular bacterial replication. L. pneumophila also manipulates host cell death and survival pathways in a way that allows continued intracellular replication.

CHEBI:17526