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Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
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336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
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299 KEGG pathways;
876 Reactome pathways;
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last update: 11 Mar, 2019

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CHEBI:18335

Name pyridoxamine 5'-phosphateC00647
Download: mol | sdf
Synonyms04'-deoxy-4'-aminopyridoxal-5'-phosphate;
Pmp;
Pyridoxamine 5'-phosphate;
Pyridoxamine 5-phosphate;
Pyridoxamine phosphate;
[4-(ammoniomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl phosphate;
Definition A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine.
Molecular Weight
(Exact mass)
248.173 (248.0562)
Molecular Formula C8H13N2O5P
SMILES Cc1ncc(COP(O)(O)=O)c(CN)c1O
InChI InChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChI Key ZMJGSOSNSPKHNH-UHFFFAOYSA-N
Crosslinking annotations KEGG:C00647 | 3DMET:B00154 | CAS:529-96-4 | ChEBI:18335 | ChEMBL:CHEMBL1235353 | KNApSAcK:C00007506 | NIKKAJI:J11.364F | PDB-CCD:PMP | PubChem:3919

Pathway ID Pathway Name Pathway Description (KEGG)
map00750Vitamin B6 metabolismNA
map01100Metabolic pathwaysNA
map04977Vitamin digestion and absorptionVitamins are a diverse and chemically unrelated group of organic substances that share a common feature of being essential for normal health and well-being. They catalyze numerous biochemical reactions. Because humans and other mammals cannot synthesize these compounds (except for some synthesis of niacin), they must obtain them from exogenous sources via intestinal absorption. Vitamins are classified based on their solubility in water or fat. Most of the water-soluble vitamins are transported across the small intestinal membrane by carrier-mediated mechanisms, but vitamin B12, cobalamin, is transported by a receptor-mediated mechanism. Intestinal absorption of fat-soluble vitamins requires all of the processes needed for fat absorption. After digestion, these vitamins and the products of pancreatic hydrolysis of triglycerides (TG) are emulsified by bile salts to form mixed micelles which are taken up by intestinal enterocytes and incorporated into chylomicrons (CM). CM are then secreted into the lymphatic system, and finally moves into the plasma.