DEPOD - human DEPhOsphorylation Database

Name	pyridoxal 5'-phosphate	Download: mol \| sdf
Synonyms	0(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl phosphate; 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde; 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate; Codecarboxylase; Phosphoric acid mono-(4-formyl-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester; Plp; Pyridoxal 5'-phosphate; Pyridoxal 5-monophosphoric acid ester; Pyridoxal 5-phosphate; Pyridoxal phosphate; Pyridoxal-5'-phosphate;
Definition	The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Molecular Weight (Exact mass)	247.1419 (247.0246)
Molecular Formula	C8H10NO6P
SMILES	[H]C(=O)c1c(COP(O)(O)=O)cnc(C)c1O
InChI	InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChI Key	NGVDGCNFYWLIFO-UHFFFAOYSA-N
Crosslinking annotations	KEGG:C00018 \| 3DMET:B00005 \| CAS:54-47-7 \| ChEBI:18405 \| ChEMBL:CHEMBL82202 \| KNApSAcK:C00007503 \| NIKKAJI:J10.690I \| PDB-CCD:PLP \| PubChem:3320

Pathway ID	Pathway Name	Pathway Description (KEGG)
map00730	Thiamine metabolism	NA
map00750	Vitamin B6 metabolism	NA
map01100	Metabolic pathways	NA
map04977	Vitamin digestion and absorption	Vitamins are a diverse and chemically unrelated group of organic substances that share a common feature of being essential for normal health and well-being. They catalyze numerous biochemical reactions. Because humans and other mammals cannot synthesize these compounds (except for some synthesis of niacin), they must obtain them from exogenous sources via intestinal absorption. Vitamins are classified based on their solubility in water or fat. Most of the water-soluble vitamins are transported across the small intestinal membrane by carrier-mediated mechanisms, but vitamin B12, cobalamin, is transported by a receptor-mediated mechanism. Intestinal absorption of fat-soluble vitamins requires all of the processes needed for fat absorption. After digestion, these vitamins and the products of pancreatic hydrolysis of triglycerides (TG) are emulsified by bile salts to form mixed micelles which are taken up by intestinal enterocytes and incorporated into chylomicrons (CM). CM are then secreted into the lymphatic system, and finally moves into the plasma.

CHEBI:18405