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KEGG Pathway - B cell receptor signaling pathway - Homo sapiens (human) Name UniProt AC Dephosphorylates following protein substrates: Dephosphorylates following non-protein substrates: INPPL1 O15357 Protein substrates of this phosphatase are not reported yet 1D-myo-inositol 1,4,5,6-tetrakisphosphate , 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate , 1D-myo-inositol 1,3,4,5-tetrakisphosphate , 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate , 1D-myo-inositol 1,2,3,4,5-pentakisphosphate , myo-inositol tetrakisphosphate , 1D-myo-inositol 1,2,3,5,6-pentakisphosphate , PPP3CB P16298 DNM1L , CRYAA , HSPB1 , JUN , MAPT , NEFH , PRKAR2A , ELK1 , FLNA , CANX , CSNK1E , GSK3B , VASP , DNM2 , RCAN1 , DNM1 , GAD2 , NFATC2 , PPP1R1A , SLC10A1 , KSR2 , SSH1 , BAD , GAD1 , PPP1R1B , TFEB , NFKBIA , LASP1 , Non-protein substrates of this phosphatase are not reported yet PTPN6 P29350 JAK2 , CTNND1 , NFAT5 , EGFR , ESR1 , NTRK1 , LCK , LYN , ROS1 , KIT , ACTN1 , SRC , CD33 , CD22 , NOS1 , HOXA10 , KDR , CASP8 , GAB2 , ERBB2 , ERBB4 , Non-protein substrates of this phosphatase are not reported yet PPP3CC P48454 DNM1L , CRYAA , HSPB1 , JUN , MAPT , NEFH , PRKAR2A , ELK1 , FLNA , CANX , CSNK1E , GSK3B , VASP , DNM2 , RCAN1 , DNM1 , GAD2 , NFATC2 , PPP1R1A , SLC10A1 , KSR2 , SSH1 , BAD , GAD1 , PPP1R1B , TFEB , NFKBIA , LASP1 , Non-protein substrates of this phosphatase are not reported yet PPP3CA Q08209 DNM1L , CRYAA , HSPB1 , JUN , MAPT , NEFH , PRKAR2A , ELK1 , FLNA , CANX , CSNK1E , GSK3B , VASP , DNM2 , RCAN1 , DNM1 , GAD2 , NFATC2 , PPP1R1A , SLC10A1 , KSR2 , SSH1 , BAD , GAD1 , PPP1R1B , TFEB , NFKBIA , LASP1 , TRPM3 , ORAI1 , Non-protein substrates of this phosphatase are not reported yet INPP5D Q92835 Protein substrates of this phosphatase are not reported yet 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate , 1D-myo-inositol 1,3,4,5-tetrakisphosphate ,
Name UniProt AC Dephosphorylated by: IKBKB O14920 PPP2CA , PPP2CB , PPM1A , PPM1B , PPM1M , CHUK O15111 PPP2CA , PPP2CB , INPPL1 O15357 PTPN1 , RAF1 P04049 CDC25A , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP5C , PTPN1 , JUN P05412 PPP3CA , PPP3CB , PPP3CC , PRKCB P05771 PHLPP1 , PHLPP2 , PPP1CA , PPP2CA , PPP2CB , LYN P07948 PTPRC , PTPRA , PTPRJ , PTPN6 , CD22 P20273 PTPN6 , NFKBIA P25963 PTPN1 , PTPN13 , PPP3CB , PPP3CC , PPP2CB , PPP2CA , PPP3CA , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , PTPN6 P29350 PTPN1 , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , AKT2 P31751 PHLPP1 , PHLPP2 , SYK P43405 UBASH3B , GSK3B P49841 EPM2A , PPP3CA , PPP3CB , PPP3CC , PTPN1 , MAP2K1 Q02750 PPP2CA , PPP2CB , RELA Q04206 PPP2CA , PPP4C , PPP2CB , NFATC2 Q13469 PPP3CA , PPP3CB , PPP3CC , CARD11 Q9BXL7 PPP2CA , PPP2CB , AKT3 Q9Y243 PHLPP1 , PHLPP2 , PPP2CA , PPP2CB ,
ChEBI ID KEGG ID ChEBIasciiName Molecule Dephosphorylated by: CHEBI:16595 C01245 1D-myo-inositol 1,4,5-trisphosphate INPP5B , INPP5A , INPP5E , INPP5J , INPP5K , OCRL , SYNJ1 , SYNJ2 , CHEBI:16618 C05981 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate TNS2 , FIG4 , INPP5B , INPP5E , INPP5K , OCRL , PTEN , PTPRQ , INPP5F , INPP5D , INPPL1 , SYNJ1 , SYNJ2 , TPTE2 ,